The Genetics of Human DZ Twinning

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Genetic contribution to DZ twinning.

The genetic contribution to dizygotic (DZ) twinning was investigated using 6,596 twin pairs from the Australian Twin Registry who provided information on other twins in their families. Responses were classified by the zygosity (DZ; monozygotic [MZ]) of the proband twins and by the relationship and zygosity of related twins. MZ probands and MZ twins reported by DZ probands were used as controls ...

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Genetics of dizygotic twinning: a feasibility study for a biobank.

To locate the genes that make a substantial contribution to variation in natural dizygotic twinning in humans, large-scale studies are needed. New studies should not stop at DNA genotyping, but collect material that allow gene-expression analysis, transcriptomics, proteomics and endocrinology. In this article we describe a pilot study to examine the feasibility, effectiveness and logistics of l...

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ژورنال

عنوان ژورنال: Twin Research and Human Genetics

سال: 2020

ISSN: 1832-4274,1839-2628

DOI: 10.1017/thg.2020.15